1. 个人基本信息,Personal basic information
姓 名:董川, Chuan Dong
政治面貌:群众,
Github:https://github.com/RiversDong
学 科: 生物信息学, Bioinformatics
电子邮件: chuand[at]zafu.edu.cn
通讯地址: 浙江省杭州市临安区武肃街666号, 浙江农林大学亚热带森林培育国家重点实验室
ADDR: No. 88 Wushu Street, Linan Hangzhou 311300, Zhejiang, P.R. China. State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University.
Google学术: https://scholar.google.com/citations?user=Q0FvyG0AAAAJ&hl=zh-CN
ResearchGate: https://www.researchgate.net/profile/Chuan-Dong
2. 研究关键字,Research Keywords
- 新基因起源和演化、机器学习、生物信息、微生物、香榧
Origins and evolution of new genes, machine learning, bioinformatics, microbiology, Torreya grandis
3. 学习教育经历,Education and learning experience
- 2010年9月—2014年7月:德州学院 应用物理学 理学学士
September 2010 - July 2014: Bachelor of Science in Applied Physics, Dezhou University - 2014年9月—2016年7月:电子科技大学 生物物理学 硕士
September 2014 - July 2016: Master of Science in Biophysics, University of Electronic Science and Technology of China - 2016年9月—2020年12月:电子科技大学 生物医学工程 工学博士
September 2016 - December 2018: Doctor of Engineering in Biomedical Engineering, University of Electronic Science and Technology of China - 2018年12月—2021年1月:芝加哥大学 新基因起源和演化 联合培养博士(国家建设高水平大学公派留学项目);
December 2018 - January 2021: Joint Doctoral Program in New Gene Origins and Evolution, University of Chicago (sponsored by the National High-level University Overseas Study Program)
4. 工作经历,Work experience
- 2021年3月—2023年8月:武汉大学 药学院 博士后
March 2021 - August 2023: Postdoctoral Researcher, School of Pharmacy, Wuhan University
5. 代表性论文,Publications
- Chuan Dong, Li Zhang, Shengqian Xia, Dylan Sosa, Deanna Arsala, Andrew G. Clark, Rod A. Wing, Manyuan Long, New gene evolution with subcellular expression patterns detected in PacBio-sequenced genomes of Drosophila genus, 2022, doi: https://doi.org/10.1101/2022.11.30.518489. (Under review).
- Jiafeng Yu, Wenwen Jiang, Sen-Bin Zhu, Zhen Liao, Xianghua Dou, Jian Liu, Feng-Biao Guo, Chuan Dong*. Prediction of protein-coding small ORFs in multi-species using integrated sequence-derived features and the random forest model. Methods, 210(1) 2023, 10-19.
- Chuan Dong, Ge-Fei Hao, Hong-Li Hua, Shuo Liu, Abraham Alemayehu Labena, Guoshi Chai, Jian Huang, Nini Rao, Feng-Biao Guo*. Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins. Nucleic Acids Research, 2018, 46(D1): D393-D398.
- Chuan Dong, Yan-Ting Jin, Hong-Li Hua, Qing-Feng Wen, Sen Luo, Wen-Xin Zheng, Feng-Biao Guo. Comprehensive review of the identification of essential genes using computational methods: focusing on feature implementation and assessment. Briefings in Bioinformatics, 2020, 21(1): 171-181.
- Chuan Dong, Zhi Zeng, Dong-Kai Pu, Qing-Feng Wen, Shuo Liu, Meng-Ze Du, Yan Sun, Yi-Zhou Gao, Nini Rao, Jian Huang, Feng-Biao Guo. CasLocusAnno: a web-based server for annotating Cas loci and their corresponding (sub) types. FEBS Letters, 2019, 593(18):2646-2654.
- Chuan Dong, Ya-Zhou Yuan, Fa-Zhan Zhang, Hong-Li Hua, Yuan-Nong Ye, Abraham Alemayehu Labena, Hao Lin, Wei Chen, Feng-Biao Guo. Combining pseudo dinucleotide composition with the Z curve method to improve the accuracy of predicting DNA elements: a case study in recombination spots. Molecular BioSystems, 2016, 12(9): 2893-2900.
- Chuan Dong, Xin Wang, Cong Ma, Zhi Zeng, Dong-Kai Pu, Shuo Liu, Candy-S Wu, Shixin Chen, Zixin Deng, Feng-Biao Guo. Anti-CRISPRdb v2. 2: an online repository of anti-CRISPR proteins including information on inhibitory mechanisms, activities and neighbors of curated anti-CRISPR proteins. Database, 2022, 2022: baac010.
- Chengchi Fang†, Chuan Dong,†, Cheng Wang, Fan Xiong, Xiaoni Gan, Liandong Yang, Honghui Zeng, Shunping He*. GageTracker: a tools for dating gene age by micro- and macro- collinearity in a high speed and accuracy (共同一作)
- Feng-Biao Guo, Chuan Dong, Hong-Li Hua, Shuo Liu, Hao Luo, Hong-Wan Zhang, Yan-Ting Jin, Kai-Yue Zhang. Accurate prediction of human essential genes using only nucleotide composition and association information. Bioinformatics, 2017, 33(12): 1758-1764.
- Yuan Huang, Jiahui Chen, Chuan Dong, Dylan Sosa, Shengqian Xia, Yidan Ouyang, Chuanzhu Fan, Dezhu Li, Emily Mortola, Manyuan Long, Joy Bergelson. Species-specific gene duplication in Arabidopsis thaliana evolved novel phenotypic effects on morphological traits under strong positive selection. The Plant Cell, 2022, 34(2): 802-817.
- Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F. Leadlay, Kui Hong, Zixin Deng, Fuling Zhou and Yuhui Sun. Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition[J]. Nature Communications, 2023, 14(1): 612.
- Qing-Feng Wen, Shuo Liu, Chuan Dong, Hai-Xia Guo, Yi-Zhou Gao, Feng-Biao Guo*. Geptop 2.0: an updated, more precise, and faster Geptop server for identification of prokaryotic essential genes. Frontiers in Microbiology, 2019, 10: 1236. (IF: 5.64).